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This lung perfusion scintigraphy shows uniform distribution of Tc-99m MAA throughout both lungs in all projections with no perfusion defects. A normal lung perfusion scan is clinically significant because:
A. It effectively rules out clinically significant pulmonary embolism
A normal lung perfusion scan has a very high negative predictive value for pulmonary embolism (>99%). Because PE causes perfusion defects, the absence of any perfusion abnormality effectively rules out a clinically significant PE. This is the primary strength of the V/Q scan: a completely normal perfusion scan provides strong evidence against PE. Lung perfusion scans use Tc-99m MAA (macroaggregated albumin), which temporarily embeds in pulmonary capillaries proportional to blood flow.
Reducing MAA Particles in Pulmonary Hypertension
Stripe Sign on a Lung Perfusion Scan
V/Q Scan in COPD: Matched Defects
V/Q Scan vs CTPA for Pulmonary Embolism in Pregnancy
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