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On a V/Q lung scan, both the ventilation and perfusion images show defects in the SAME region (a 'matched' defect). By PIOPED II criteria, a matched ventilation-perfusion defect in the setting of a normal or near-normal chest X-ray is most consistent with:
B. Low probability for pulmonary embolism
A matched V/Q defect — where both ventilation and perfusion are reduced in the same lung region — is characteristic of parenchymal lung disease (COPD, pneumonia, mucus plug), not PE. PE causes perfusion loss without ventilation loss (mismatch). According to PIOPED II criteria, matched defects with a normal or near-normal CXR are LOW probability for PE. Low probability does not mean zero risk — clinical probability must be integrated.
Normal Lung Perfusion Scan and Pulmonary Embolism
Reducing MAA Particles in Pulmonary Hypertension
Stripe Sign on a Lung Perfusion Scan
V/Q Scan in COPD: Matched Defects
V/Q Scan vs CTPA for Pulmonary Embolism in Pregnancy
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