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NMTCB PET · SPECIALTY EXAM GUIDE

NMTCB PET exam guide

Who can sit the PET specialty exam, how it is structured, what each content area asks about, and how the seven-year credential is renewed.

Updated October 2026

The exam at a glance

NMTCB PET
Questions225: 200 scored + 25 unscored pretest items
Time3 hours 45 minutes
FormatComputer-based, four-option multiple choice, same length for every candidate
Test centersIQT
Fee$225 examination processing fee
CredentialThe right to use “PET” after your name
Valid forSeven years, renewed annually in between

Source: NMTCB PET exam information. Check the board’s page before you apply — fees and policies change.

Who can sit it

Route 1: certified nuclear medicine technologists

An active NMTCB CNMT, ARRT(N) or CAMRT(RTNM) certification, plus a minimum of 700 hours of clinical experience as a certified or registered nuclear medicine technologist on a dedicated PET, PET/MR or PET/CT scanner.

Route 2: radiographers and radiation therapists

An active ARRT(R), ARRT(T), CAMRT(RT) or CAMRT(RTT) certification together with an active CT or MRI certification from a nationally recognized board. On top of that:

What is on the exam

Content areaShareOf 200 scored
Diagnostic procedures35%~70
Instrumentation and quality control30%~60
Radiopharmaceuticals25%~50
Radiation protection10%~20

Diagnostic procedures (35%)

FDG oncology imaging dominates: patient preparation (fasting, a blood glucose check before injection, limiting exercise and keeping the patient warm to reduce brown fat uptake), the uptake period, normal biodistribution in brain, myocardium and urinary tract, and the benign causes of uptake — infection, inflammation, muscle and brown fat — that mimic disease. Expect response assessment such as the Deauville scale in lymphoma, neurologic FDG patterns, cardiac PET perfusion and FDG viability, and the receptor-targeted studies: somatostatin receptor imaging with Ga-68 DOTATATE and PSMA imaging in prostate cancer.

Instrumentation and quality control (30%)

Coincidence detection of the two 511 keV annihilation photons emitted roughly 180° apart, detector crystals, time-of-flight, and corrections for randoms, scatter and attenuation. CT-based attenuation correction and its artifacts — respiratory misregistration, metal, dense contrast and truncation — are reliable exam material, as is QC: daily detector checks, normalization, and cross-calibration between the scanner and the dose calibrator, which SUV accuracy depends on.

Radiopharmaceuticals (25%)

Half-lives and production routes: F-18 (about 110 minutes, cyclotron), C-11 (about 20 minutes), N-13 (about 10 minutes), O-15 (about 2 minutes), Ga-68 (about 68 minutes, from a Ge-68/Ga-68 generator) and Rb-82 (about 75 seconds, from a Sr-82/Rb-82 generator that needs strontium breakthrough testing). Know FDG’s mechanism — uptake by glucose transporters, phosphorylation by hexokinase and trapping as FDG-6-phosphate — and how the standardized uptake value is calculated.

Radiation protection (10%)

511 keV photons penetrate far more than Tc-99m’s 140 keV, so time, distance and shielding change: thicker shielding, tungsten syringe shields, and treating the patient as a significant source throughout the uptake period. Expect dose limits, surveys, and the handling and transport rules that apply to positron emitters.

Content shares from NMTCB PET exam information. Topic notes are our own summary of the outline, not NMTCB wording.

Keeping the credential

The PET credential has to be renewed every year, and your primary certification must stay active alongside it. It is time limited: after seven years it expires unless you renew it by re-examination or by documenting 42 hours of PET-specific continuing education earned during that seven-year cycle. Both routes need an application and a fee, so track those hours from the start rather than reconstructing them in year seven.

Common questions

How many questions are on the NMTCB PET exam?
225: 200 scored and 25 unscored pretest items, with three hours and 45 minutes to complete them.
How many clinical hours do I need for the NMTCB PET exam?
For certified nuclear medicine technologists, a minimum of 700 hours on a dedicated PET, PET/MR or PET/CT scanner. The route for radiographers and radiation therapists requires 1,000 hours plus coursework.
How much does the NMTCB PET exam cost?
The examination processing fee is $225.
How long is the NMTCB PET credential valid?
Seven years, with annual renewal in between. At the end you renew by re-examination or 42 hours of PET-specific continuing education.
Is the NMTCB PET exam adaptive?
No. Every candidate answers the same 225 questions, unlike the NMTCB nuclear medicine exam.

Practise PET questions that explain the why

200 NMTCB PET questions weighted 35/30/25/10 to the board’s outline, plus 34 PET case studies, each with a worked explanation. 25 questions are free, no card and no account.

See the PET question bank

Related

Free NMTCB PET practice questions with answers →

How to become a CNMT →

NMTCB vs ARRT(N) →

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